Windy Bar Island Conservation Area does not have road access and cannot be reached by automobile. It can be accessed by watercraft from Red Star Access (a Mississippi River boat launch), which is located on Second Street just north of the Cape Girardeau downtown district and one block east of Main Street. The southern end of Windy Bar Island is four river miles north of Red Star Access. Windy Bar Island can also be reached by watercraft from the Moccasin Springs Boat Ramp at Trail of Tears State Park. The northern end of Windy Bar Island is 4.50 miles south of the Trail of Tears State Park boat launch.